Situation of the Covid-19 epidemic in patients on peritoneal dialysis on 2020/05/15 in France : RDPLF data-base

Keywords: SARS-CoV-2, Peritoneal dialysis, France, pandemia, COVID-19

Abstract

Numerous studies have shown that chronic renal failure, whatever the treatment, is an important risk factor during the SARS-Cov2 pandemic. We present the incidence of COVID-19 infection, and its lethality, in France according to data from the French Language Peritoneal Dialysis Registry (RDPLF), during the period of the epidemic peak between March 1 and May 15, 2020.

Of the 3,104 patients treated with PD during this period, from 156 centers, 59 contracted COVID-19, ie 1.8%, a percentage significantly lower than that observed in center hemodialysis. Diabetes was found in 64% of infected patients while it was only present in 36% of uncontaminated patients. The mode of contamination was attributed to a hospital stay in 19% of the cases, a family infection in 17% of the cases, treatment in nursing homes in 15% of the cases, unknown in 44% of the cases. Sixty-two percent of the infected patients were on assisted PD, without identifying the source of contamination. The mortality rate was high at 40%, comparable to other countries in PD. A comparison with hemodialysis could only be made after adjustment for comorbidities and patient profiles: data on hemodialysis are not available in the RDPLF.

Home peritoneal dialysis decreases the risk of Covid-19 contamination, but associated comorbidities and age are the source of high mortality. Non-autonomous patients have a higher risk of contamination.

References

Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Zhonghua Liu Xing Bing Xue Za Zhi Zhonghua Liuxingbingxue Zazhi. 10 févr 2020;41(2):145‑51.

Geneva:World Hearth organization, 2020. WHO Director-General’s opening remarks at the media briefing on COVID-19 [Internet]. 2020. Disponible sur: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200311-sitrep-51-c ovid-19.pdf?sfvrsn=1ba62e57_10

Direction générale de la santé. Point de situation de la direction générale de la santé (DGS) sur l’épidémie de coronavirus COVID-19 [Internet]. 2020. Disponible sur: https://solidarites-sante.gouv.fr/soins-et-maladies/maladies/maladies-infectieuses/coronavirus/etat-des-lieux-et-actualites/article/points-de-situation-coronavirus-covid-19#Point-du-vendredi-15-mai-2020

Agence de la BioMedecine. Situation de l’épidémie de Covid-19 chez les patients dialysés et greffés rénaux en France [Internet]. 2020. Disponible sur: https://www.agence-biomedecine.fr/R-E-I-N-Reseau-Epidemiologique-et- Information-en-Nephrologie

Lescure F-X, Bouadma L, Nguyen D, Parisey M, Wicky P-H, Behillil S, et al. Clinical and virological data of the first cases of COVID-19 in Europe: a case series. Lancet Infect Dis. 2020;20(6):697‑706.

Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 26 févr 2020;200642.

The Renal Association. COVID-19 surveillance report for renal centres in the UK [Internet]. 2020. Disponible sur: https://renal.org/covid-19/ra-resources-renal-professionals/

Sánchez-Álvarez JE, Pérez Fontán M, Jiménez Martín C, Blasco Pelícano M, Cabezas Reina CJ, Sevillano Prieto ÁM, et al. SARS-CoV-2 infection in patients on renal replacement therapy. Report of the COVID-19 Registry of the Spanish Society of Nephrology (SEN). Nefrol Publicacion Of Soc Espanola Nefrol. 16 avr 2020;

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet Lond Engl. 28 2020;395(10229):1054‑62.

Trujillo H, Caravaca-Fontán F, Sevillano Á, Gutiérrez E, Caro J, Gutiérrez E, et al. SARS-CoV-2 Infection in Hospitalized Patients with Kidney Disease. Kidney Int Rep. 1 mai 2020;

Ikizler TA, Kliger AS. Minimizing the risk of COVID-19 among patients on dialysis. Nat Rev Nephrol. 2020;16(6):311‑3.

Published
2020-06-15
How to Cite
1.
Nouvier M, Verger C, Fouque D. Situation of the Covid-19 epidemic in patients on peritoneal dialysis on 2020/05/15 in France : RDPLF data-base. Bull Dial Domic [Internet]. 2020Jun.15 [cited 2020Jul.12];3(2):73-1. Available from: https://www.bdd.rdplf.org/index.php/bdd/article/view/55433