Peritoneal catheter infections : data from the French language peritoneal dialysis registry (RDPLF), risk factors




peritoneal dialysis, peritoneal dialysis catheter, catheter infection, dialyse péritonéale, cathéter dialyse péritonéale


Peritoneal catheter infections : data from the French language peritoneal dialysis registry (RDPLF), risk factors

The French Language Peritoneal Dialysis Registry (RDPLF) record since 1997 all data dealing with peritoneal catheter insertion and follow up.

The aim of this study is to analyze catheter infections on 10801 catheters in 144 centres from January 1, 1997 and December 31, 2018.

Infections are more common in the first month and 50% occur before the tenth month. The risk of infection increases in case of wall hematoma, initial fluid leakage, and obesity. It decreases with the use of prophylactic antibiotics at the time of catheter insertion, with experienced operator, if the first dressing is delayed for 7 days, and with mupirocin as exit-site prophylaxis.

During last two decades the percentage of Staphylococcus aureus infections has decreased, whereas the proportion of Pseudomonas, Corynebacterium and other Gram + cocci increased.

The incidence of catheter infections is low compared to literature data: it decreased to 0.16 episodes per year for the 2013-2017 period.

Adherence to ISPD guidelines: preoperative antibioprophylaxis is the most followed guideline (70.7% of catheter implantations in 2018). Local antibioprophylaxis concerns only 15.6% of catheters, and remains concentrated in a few centres ; mupirocin is the most frequently used agent. Screening for nasal carriage of S. aureus is performed in only 42% of cases.

The catheter section of the RDPLF has allowed the follow-up of clinical practices incidence of infections and ecology for 21 years, both at the national and center level Our study confirms a wide variability in clinical practices, compared to ISPD guidelines.


The association between exit-site infection and subsequent peritonitis among peritoneal dialysis patients. Van Diepen AT, Tomlinson GA, Jassal SV. Clin J Am Soc Nephrol 2012; 7 :1266-71

Recent peritonitis associates with mortality among patients treated with peritoneal dialysis. J Am Soc Nephrol 2012; 23(8) :1398-1405

The risk of peritonitis after an exit-site infection : a time-matched, case-control study. Nephrol Dial Transplant 2013 ;28 :1915-1921

Peritoneal dialysis access associated infections. Bieber S, Mehrotra R. Adv Chronic Kidney Dis 2019; 26 :23-29

Microbiological surveillance of peritoneal dialysis associated peritonitis : antimicrobial susceptibility profiles of a referral center in Germany over 32 years. Kitterer D, Latus J, Pöhlmann C, Alscher MD, Kimmel M. PLOS ONE 2015 ; doi :10.1371/journal.pone.0135969

Microbiology of peritoneal dialysis-related infection and factors of refractory peritoneal dialysis related peritonitis: A ten-year single-center study in Taiwan. Wang HH, Huang CH, Kuo MC, Lin SY, Hsu CH, Lee CY, Chiu YW, Chen YH, Lu PL. Journal of Microbiology, Immunology and Infection, 10.1016/j.jmii.2018.10.013

ISPD Catheter-Related Infection Recommendations : 2017 update. Szeto CC, Li PK, Johnson DW, Bernardini J, Dong T, Figueiredo AE, Ito Y, Kazacioglu R, Moraes T, Van Eich S, Brown EA. Perit Dial Int 2017; 37(2) :141-154

ISPD Guidelines/Recommendations : creating and maintaining optimal peritoneal dialysis access in the adult patient : 2019 update. Crabtree JH, Shrestha BM, Chow KM, Figueiredo AE, Poulsen JV, Wilkie M, Abdel-Aal A, Cullis B, Goh BL, Briggs VR, Brown EA, Dor FJMF. Perit Dial Int 2019; doi :10.3747. Traduction française : Bulletin de Dialyse à Domicile Vol 2 no 2(2019) 96-116.

Catheter insertion and perioperative practices within the ISPD North American Research Consortium. Wallace EL, Fissell RB, Golper TA, Blake PG, Lewin AM, Oliver MJ, Quinn RR. Perit Dial Int 2016; 36(4) :382-386

Regional variation in the treatment and prevention of peritoneal dialysis-related infections in the Peritoneal Dialysis Outcomes and Practice Patterns Study. Boudville N, Johnson DW, Zhao J, Bieber BA, Pisoni RL, Piraino B, Bernardini J, Nessim ST, Ito Y, Woodrow G, Brown F, Collins J, Kanjanabuch T, Szeto CC, PerlJ. Nephrol Dial Transplant 2018; doi :10.1093/ndt/gfy204

Risk predictors and causes of technique failure within the first year of peritoneal dialysis : an Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) study. See EJ, Johnson DW, Hawley CM, Pascoe EM, Badve SV, Boudville N, Clayton PA, Sud K, Polkinghorne KR, Borlace M, Cho Y. Am J Kidney Dis 2017; 72(2) :188-197

Assessment of current practice and barriers to antimicrobial prophylaxis in peritoneal dialysis patients. Campbell DJ, Brown FG, Craig JC, Gallagher MP, Johnson DW, Kirkland GS, Kumar SK, Lim WH, Ranganathan D, Saweirs W, Sud K, Toussaint ND, Walker RG, Williams LA, Yehia M, Mudge DW. Nephrol Dial Transplant 2016; 31(4) :619-627

Peritoneal dialysis practice in Australia and New Zealand : a call to action. Jose MD, Johnson DW, Mudge DW, Tranaeus A, Voss D. Nephrology 16 , 2011 ;19-29 ; doi : 10.1111/j.1440-1797.2010.01390.x

Peritoneal dialysis practice in Australia and New Zealand : a call to sustain the action. Mudge DW, oudville N, Brown F, Clayton P, Duddington M, Holt S, Johnson DW, Jose M, Saweirs W, Sud K, Voss D, Walker R . Nephrology 21, 2016 ; 535-546 ; doi : 10.1111/nep.12731

Infection prophylaxis in peritoneal dialysis patients : results from an Australia/New Zealand Survey. Campbell DJ, Mudge DW, Gallagher MP, Lim WH, Ranganathan D, Saweirs W, Craig JC. Perit Dial Int 2017; 37 :191-197

Efficacy of prophylactic antibiotics at peritoneal catheter insertion on early peritonitis : data from the Catheter Section of the French Language Peritoneal Dialysis Registry. Lanot A, Lobbedez T, Bechade C, Verger C, Fabre E, Dratwa M, Vernier I. Am J Nephrol 2016;44:419-425

Center-specific factors associated with peritonitis risk – a multicenter registry analysis. Nadeau-Fredette AC, Johnson DW, Hawley CM, Pascoe EM, Cho Y, Clayton PA, Borlace M, Badve SV, Sud K, Boudville N, McDonald SP. Perit Dial Int 2016;36(5):509-18. doi :10.3747/pdi.2015.00146

Multicenter registry analysis of center characteristics associated with technique failure in patients on incident peritoneal dialysis. Htay H, Yeoungjee C, Pascoe EM, Darssan D, Nadeau-Fredette AC, Hawley C, Clayton PA, Borlace M, Badve SV, Sud K, Boudville N, McDonald SP, Johnson DW. Clin J Am Soc Nephrol 12, 2017 ; doi :

Clusters of practice in peritoneal dialysis in France: data from the catheter section of the RDPLF. Lanot A, Bechade C, Verger C, Fabre E, Vernier I, Lobbedez T. Perit Dial Int 2017; doi :10.3747/pdi.2017.00135



How to Cite

Vernier I, Fabre E, Dratwa M, Verger C. Peritoneal catheter infections : data from the French language peritoneal dialysis registry (RDPLF), risk factors. Bull Dial Domic [Internet]. 2019 Aug. 13 [cited 2024 Jun. 13];2(3):135-41. Available from: