Acid base status of prevalent peritoneal dialysis patients

RDPLF data


  • Raymond Azar Service de Néphrologie Dialyse, Centre hospitalier 130 ave L Herbeaux 59385 Dunkerque (France)
  • Vincent Coevoet DIM, Centre hospitalier 130 ave L Herbeaux 59385 Dunkerque (France)



acide base status, peritoneal dialysis, RDPLF, acid base status, nutrition, acidosis, acidose, status acido-basique


Acid-base status of patients on peritoneal dialysis is influenced by multiple factors. Metabolic acidosis is a common feature of chronic renal failure and dialysis treatment provides alkali in the dialysate in order to maintain a normal acid-base balance. This paper reports the prevalence of acid-base disorders in peritoneal dialysis patients and their associations with clinical and laboratory parameters. This is a cross-sectional retrospective study that included all PD patients registered in the RDPLF database. Metabolic acidosis was found in 20.4% of patients while 27.8% of patients had metabolic alkalosis. There is a significant relationship between age, protein intake estimated by nPNA and the level of alkaline reserve pleading in favor of the influence of dietary intakes in the maintenance of metabolic acidosis. Low residual renal function is associated with a lower probability of being in metabolic alkalosis. These results could allow an individual choice of the dialysate buffer in order to permanently obtain stable acid-base status in patients on peritoneal dialysis.



How to Cite

Azar R, Coevoet V. Acid base status of prevalent peritoneal dialysis patients: RDPLF data. Bull Dial Domic [Internet]. 2018 Mar. 13 [cited 2023 Mar. 30];1(1):21-5. Available from: